Pure Crystalline Choline Chloride (98% - 100%)
At Meden Pharma Pvt. Ltd., we manufacture high-purity crystalline Choline Chloride conforming strictly to the pharmacopoeia standards of the **Indian Pharmacopoeia (IP)** and **United States Pharmacopeia (USP)**. This grade is synthesized using superior chemical controls to ensure the absolute minimum presence of heavy metals and free amines.
Chemical & Physical Parameters:
- Chemical Formula: C5H14ClNO
- Molecular Weight: 139.63 g/mol
- Chemical Name: 2-hydroxyethyl-trimethyl ammonium chloride
- Melting Point: 244 °C – 247 °C (471 °F – 477 °F)
- State of Matter: White hygroscopic crystal powder
- Synthesis: Trimethylamine (TMA) + Ethylene Oxide (EO) + HCl
Importance in Human Nutrition & Metabolism
Choline is a critical dietary nutrient found naturally in food groups as free choline and in esterified forms like phosphocholine. It operates as an indispensable precursor for acetylcholine (vital for neurological impulse transmission), cell phospholipids, and the methyl group donor betaine.
It is vital for safeguarding the structural integrity of cell membranes, transmembrane signaling, and lipid/cholesterol transport. Inadequate dietary absorption of choline triggers liver dysfunction, indicated clinically by elevated serum alanine aminotransferase (ALT) levels. Therefore, our pure IP/USP grade is widely utilized in therapeutic vitamins, infant formulas, and clinical supplements.
Technical Specifications (IP / USP Grade)
| Technical parameters | Standard Specifications Limits |
|---|---|
| Appearance | White hygroscopic crystalline powder with slight odor of amines |
| Choline Chloride Content (Dry Basis) | 98.0% – 100.5% |
| Choline Content (Dry Basis) | 72.0% – 74.5% |
| Free Trimethylamine (TMA) | < 500 PPM |
| Heavy Metals (as Pb) | ≤ 10 PPM |
| Residue on Ignition | ≤ 0.1% |
| Packaging Option | 25 Kg HDPE bag with double PE inner liners |
Request Certificate of Analysis (CoA)?
We supply batch CoAs and manufacturing process declarations on request.